5-bromo-2-chloro-4’-ethoxydiphenylmethane
- CasNo:461432-23-5
Product Description
5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5 with purity >99% Low price in stock
- Molecular Formula: C15H14BrClO
- Molecular Weight: 325.633
- Boiling Point: 392.976 °C at 760 mmHg
- Flash Point: 191.465 °C
- PSA： 9.23000
- Density: 1.371 g/cm3
- LogP: 5.09200
461432-23-5 Relevant articles
Synthesis method for preparing 5-bromo-2-chloro-4'-ethoxydiphenylmethane
-
, (2022/04/08)
The present invention relates to a metho...
PREPARATION OF HIGHLY PURE AMORPHOUS DAPAGLIFLOZIN
-
Page/Page column 24, (2021/12/13)
A novel and improved process for the pre...
Synthesis method of dapagliflozin intermediate 5-bromo-2-chloro-4 '-ethoxydiphenylmethane
-
, (2020/04/06)
The invention discloses a synthesis meth...
Preparation method of 5-bromo-2-chloro-4 '-ethoxydiphenylmethane
-
Paragraph 0034; 0038; 0044-0060, (2020/09/23)
The invention relates to a preparation m...
461432-23-5 Process route
-
-
5-bromo-2-amino-4'-ethoxydiphenylmethane
-
![4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene](/upload/2026/10/067daaf192b94261beca14f2f1ded6f3_0c52e519-d07f-4185-830d-3a186a5cff5d.png)
-
461432-23-5
4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
| Conditions | Yield |
|---|---|
|
5-bromo-2-amino-4'-ethoxydiphenylmethane;
With
hydrogenchloride; sodium nitrite;
In
water;
at -5 - 0 ℃;
for 3h;
Large scale;
With
hydrogenchloride; copper(l) chloride;
In
water;
at 20 - 80 ℃;
for 4h;
Large scale;
|
83%
|
|
5-bromo-2-amino-4'-ethoxydiphenylmethane;
With
hydrogenchloride; sodium nitrite;
In
water;
at -5 ℃;
for 3h;
Industrial scale;
With
copper(l) chloride;
In
water;
at 20 - 80 ℃;
for 4h;
Industrial scale;
|
83%
|
|
5-bromo-2-amino-4'-ethoxydiphenylmethane;
With
hydrogenchloride; sodium nitrite;
In
water;
at -5 - 0 ℃;
for 3h;
Large scale;
With
hydrogenchloride; copper(l) chloride;
In
water;
at 20 - 80 ℃;
for 3h;
Large scale;
|
79%
|
-
-
4-bromo-1-chloro-2-(chloromethyl)benzene
-
-
103-73-1
Phenetole
-
-
461432-23-5
4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene
| Conditions | Yield |
|---|---|
|
With
aluminum (III) chloride;
In
ethyl acetate;
at 78 ℃;
for 9h;
Cooling with ice;
Large scale;
|
89%
|
461432-23-5 Upstream products
-
461432-22-4
(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone
-
107-06-2
1,2-dichloro-ethane
-
21739-92-4
5-bromo-2-chlorobenzoic acid
-
103-73-1
Phenetole
461432-23-5 Downstream products
-
461432-24-6
(3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol
-
960494-15-9
C33 H57 ClO7 Si4
-
864070-18-8
4-(5-bromo-2-chlorobenzyl)phenol
-
714269-57-5
(2S,3R,4S,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)-2-methoxy-tetrahydropyran-3,4,5-triol