Neratinib Maleate
- CasNo:915942-22-2
Product Description
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1.What is the Neratinib Maleate ?
Neratinib (HKI-272) is a pan-HER inhibitor, this irreversible tyrosine kinase inhibitor binds and inhibits the tyrosine kinase activity of epidermal growth factor receptors, EGFR (or HER1), HER2 and HER4, which leads to reduced phosphorylation and activation of downstream signaling pathways.
Neratinib Maleate is a codrug; used in preparation of heterobifunctional PROTAC compounds as degraders of estrogen receptor.
2.What is the CAS number for Neratinib Maleate ?
The CAS number of Neratinib Maleate is 915942-22-2.
More information of Neratinib Maleate 915942-22-2 are:
|
CAS?Number |
915942-22-2 |
|
PSA |
187.00000 |
|
LogP |
5.79028 |
3.What is the molecular formula of Neratinib Maleate ?
The chemical formula of?Neratinib Maleate is C30H29ClN6O3.C4H4O4 which containing 34 Carbon atoms,33 Hydrogen atoms,1 Chlorine atoms,6 Nitrogen atoms and 5 Oxygen atoms,and the molecular weight, and the molecular weight of Neratinib Maleate is 673.11500
4.What is Neratinib Maleate(915942-22-2)used for?
Neratinib (HKI-272) is a pan-HER inhibitor, this irreversible tyrosine kinase inhibitor binds and inhibits the tyrosine kinase activity of epidermal growth factor receptors, EGFR (or HER1), HER2 and HER4, which leads to reduced phosphorylation and activation of downstream signaling pathways.
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5.Good factory exports good Neratinib Maleate 915942-22-2
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