Docetaxel
- CasNo:125354-16-7
Product Description
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1.What is the Docetaxel ?
Docetaxel is a semisynthetic derivative of Paclitaxel, an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. It is available in single-dose vials for intravenous administration and is widely distributed with the highest concentration in the hepatobiliary system. Docetaxel is highly plasma protein bound and primarily eliminated in the feces with a terminal half-life of 11 hours.
2.What is the CAS number for Docetaxel ?
The CAS number of Docetaxel is 125354-16-7.
3.What are another words for Docetaxel ?
Synonyms?for?Docetaxel 125354-16-7:N-Debenzoyl-N-(tert-butoxycarbonyl)taxol;
4.What is Docetaxel (125354-16-7) used for?
Docetaxal (Docetaxel EP Impurity G) is an impurity of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel (P132500). Docetaxel is an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin.
InChI:InChI=1/C45H55NO15/c1-23-28(58-39(53)33(50)32(26-16-12-10-13-17-26)46-40(54)61-41(4,5)6)21-45(55)37(59-38(52)27-18-14-11-15-19-27)35-43(9,29(49)20-30-44(35,22-56-30)60-25(3)48)36(51)34(57-24(2)47)31(23)42(45,7)8/h10-19,28-30,32-35,37,49-50,55H,20-22H2,1-9H3,(H,46,54)/t28-,29-,30+,32-,33+,34+,35-,37-,43+,44-,45+/m0/s1
Relevant articles related to Docetaxel:
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Article |
Source |
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Synthesis of docetaxel and butitaxel analogues through kinetic resolution of racemic β-lactams with 7-O-triethylsilylbaccatin III |
Ge, Haibo,Spletstoser, Jared T.,Yang, Yan,Kayser, Margaret,Georg, Gunda I. , p. 756 - 759 (2007) |
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Novel crystalline forms of anticancer compound CX1409 and preparation method and application of novel crystalline forms of anticancer compound CX1409 |
- Paragraph 0054-0055; 0058, (2018/04/01) |
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Anticancer compound CX1409 dihydrate and DMSO solvate of the new crystal and its preparation method and application (by machine translation) |
- Paragraph 0075; 0076; 0079, (2018/03/25) |
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