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2-Chloro-4-fluorobenzoic acid

  • CasNo:2252-51-9

Product Description

Buy Quality 2-Chloro-4-fluorobenzoic acid 2252-51-9 In Stock with Immediately Delivery

  • Molecular Formula: C7H4ClFO2
  • Molecular Weight: 174.559
  • Appearance/Colour: white powder or flakes 
  • Vapor Pressure: 0.00308mmHg at 25°C 
  • Melting Point: 181-183 °C(lit.) 
  • Boiling Point: 271.9 °C at 760 mmHg 
  • PKA: 2.90±0.25(Predicted) 
  • Flash Point: 118.2 °C 
  • PSA: 37.30000 
  • Density: 1.477 g/cm3 
  • LogP: 2.17730 

2-Chloro-4-fluorobenzoic acid(Cas 2252-51-9) Usage

InChI:InChI=1/C7H4ClFO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,(H,10,11)/p-1

2252-51-9 Relevant articles

Stepwise benzylic oxygenation via uranyl-photocatalysis

Hu, Deqing,Jiang, Xuefeng

supporting information, p. 124 - 129 (2022/01/19)

Stepwise oxygenation at the benzylic pos...

Chlorobenzene-pyridine compounds and application thereof

-

Paragraph 0099; 0101; 0102; 0103, (2018/04/01)

The invention relates to chlorobenzene-p...

Flow carbonylation of sterically hindered ortho-substituted iodoarenes

Mallia, Carl J.,Walter, Gary C.,Baxendale, Ian R.

supporting information, p. 1503 - 1511 (2016/08/02)

The flow synthesis of ortho-substituted ...

2-chloro-4-fluorobenzoic acid and preparation method thereof

-

Paragraph 0041-0042, (2017/04/03)

The invention discloses 2-chloro-4-fluor...

2252-51-9 Process route

carbon monoxide
201230-82-2

carbon monoxide

2-chloro-4-fluoro-1-iodobenzene
101335-11-9

2-chloro-4-fluoro-1-iodobenzene

2-choro-4-fluorobenzoic acid
2252-51-9

2-choro-4-fluorobenzoic acid

Conditions
Conditions Yield
With water; palladium diacetate; triethylamine; triphenylphosphine; In 1,4-dioxane; at 110 ℃; for 2h; under 11251.1 Torr; Flow reactor;
89%
4-amino-2-chlorobenzoic acid
2457-76-3

4-amino-2-chlorobenzoic acid

2-choro-4-fluorobenzoic acid
2252-51-9

2-choro-4-fluorobenzoic acid

Conditions
Conditions Yield
4-amino-2-chlorobenzoic acid; With dihydrogen peroxide; In water; at 40 - 50 ℃; for 3h; Ionic liquid;
With potassium fluoride; In water; at 40 - 50 ℃; for 3h; Temperature;
97.5%

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